Marfan Syndrome
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How is Marfan Syndrom Inherited?
-Either parent can pass on the gene
-the offspring only needs to inherit
ONE
copy of the mutation
-the mutation is
DOMINANT;
dominant genes
ALWAYS
show up
-
The Fibrillin gene (FBN1) can mutate before birth
Marfan Syndrome Pedigree
What is a pedigree?
-The history of a person's family; usually used to determine how a genetic disease is inherited throughout a family
What is this pedigree showing?
1) the mother has the
dominant
allele that
codes for marfan syndrome
2)
one of their daughters and one of their sons
inherited the dominant allele that codes for Marfan syndrome
3) their son then
passed that dominant allele onto his son
Home
Basic Information
Organ Systems
Pathology
Etiology
The Skeletal System
Treatments
Biotech
Interesting Facts
Works Cited